A collision on the A22 at Whitesmith on Friday (June 10) has left a 29-year-old motorcycle rider with life-threatening injuries.
Emergency services arrived at the scene at around 4.45pm following reports of the collision between a black Honda motorcycle and a black Kia Rio car.
The motorbike rider was attended to by paramedics and taken to hospital.
Officers would like to speak to anybody who witnessed the incident, the circumstances leading up to it or has any relevant dash cam footage.
Contact police via collision.appeal@sussex.police.uk, quoting Op Cornfield.